Understanding Urinary Tract Infections: Causes, Symptoms, and Effective Treatments
Yulia Shevchenko
Yulia Shevchenko 1 year ago
Medical Doctor, Health Writer #Healthy Lifestyle & Wellness
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Understanding Urinary Tract Infections: Causes, Symptoms, and Effective Treatments

Urinary tract infections (UTIs) are inflammatory conditions caused by microorganisms entering the urethra, bladder, ureters, or kidneys.

If you frequently feel the urge to urinate accompanied by a fever, it might be time to consult a healthcare professional.

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What Are Urinary Tract Infections (UTIs)?

UTIs are inflammatory diseases that occur when microorganisms invade the urethra (urethritis), bladder (cystitis), ureters, or kidneys (pyelonephritis). Women are four times more likely than men to develop these infections, although the incidence in men increases after age 50.

How Do Urinary Tract Infections Develop?

Inflammation is most commonly triggered by Escherichia coli bacteria residing in the rectum. In women, the urethral opening is located close to the anus, making infection easier. Additionally, the short length of the female urethra allows bacteria to quickly reach the bladder. This short urethra also makes women more susceptible to sexually transmitted infections (STIs) such as chlamydia, gonorrhea, herpes, or mycoplasma that can cause inflammation.

In men, E. coli can also enter the urethra from the rectum, but inflammation often arises from chronic prostatitis. An enlarged prostate compresses the bladder neck, preventing complete emptying. This urine retention fosters bacterial growth and infection of the urinary tract.

Factors Increasing the Risk of UTIs

UTIs are more common under the following conditions:

  • Frequent change of sexual partners, increasing exposure to STIs.
  • Use of certain lubricated contraceptives. Condoms, diaphragms, or spermicides can spread bacteria across the external genitalia during vigorous activity.
  • Menopause. Estrogen supports urinary tract tone and healthy vaginal flora. Hormone levels decline approaching menopause, making the urinary tract more vulnerable to infections.
  • Kidney stones. They obstruct urine flow, raising infection risk.
  • Weakened immune system. Conditions like diabetes or immune disorders reduce natural defenses against microbes.
  • Congenital urinary tract abnormalities. Structural issues can cause urine stagnation due to narrowing or twisting.
  • Use of urinary catheters. These tubes, inserted through the urethra into the bladder for bedridden patients, can introduce bacteria.
  • Urinary tract surgeries. Procedures carry a risk of infection.

Symptoms Based on Infection Location

Symptoms may not always be obvious, especially in older adults, where infections can be asymptomatic. However, most experience dysuria symptoms such as:

  • Persistent urge to urinate.
  • Burning sensation during urination.
  • Frequent bathroom visits with small urine volumes.
  • Cloudy urine with an unpleasant odor.
  • Urine discoloration—red, pink, or dark like cola—indicating blood presence.

Additional symptoms depend on which part of the urinary tract is infected.

Urethritis

This infection affects the urethra and typically causes dysuria. Sometimes, there are discharges from the urethra, but fever and malaise are usually absent.

Cystitis

Bladder inflammation causes pelvic or suprapubic pain and discomfort. Occasionally, blood may appear in urine. Generally, it does not significantly impact daily activities.

Pyelonephritis

Kidney infection presents with severe lower back or flank pain, fever, and chills. Nausea and vomiting may also occur.

Potential Complications of UTIs

Possible complications include:

  • Progression to chronic infection if untreated, especially with multiple episodes within six months to a year.
  • Kidney damage from pyelonephritis leading to acute or chronic renal failure, which can be life-threatening.
  • Abscess formation near the kidney or bloodstream infection (sepsis), a potentially fatal condition.
  • Pregnancy complications. UTIs during pregnancy increase the risk of low birth weight or premature delivery.
  • Urethral stricture in men due to recurrent inflammation causing narrowing from connective tissue growth.

What To Do If You Notice UTI Symptoms

Consult a general practitioner who may diagnose or refer you to a urologist.

Diagnostic methods include:

  • Urinalysis to detect white and red blood cells and bacteria, confirming inflammation.
  • Bacterial culture by growing urine samples on nutrient media to identify bacteria and determine antibiotic sensitivity.
  • Imaging such as ultrasound, CT scan, or MRI to examine urinary tract structures.
  • Cystoscopy, inspecting the bladder interior with a thin flexible tube equipped with a camera.

How Are UTIs Treated?

Antibiotics are prescribed to eradicate bacteria. Over-the-counter pain relievers may be recommended to ease symptoms.

Severe infections may require hospitalization for intravenous antibiotics.

For recurrent infections, doctors might prescribe low-dose antibiotics for a six-month course.

Sexually active women may receive a single antibiotic dose after intercourse. Hormone therapy with estrogen might be advised during menopause.

Preventing Urinary Tract Infections

Experts at Mayo Clinic suggest the following preventive measures:

  • Drink plenty of fluids, especially water, to dilute urine and increase urination frequency, flushing out bacteria.
  • Consume cranberry juice, which acidifies urine, inhibiting bacterial growth and lowering infection risk.
  • Maintain proper hygiene by wiping from front to back after urination and bowel movements.
  • Empty the bladder soon after sexual activity to flush out potential bacteria.
  • Avoid irritating feminine products and refrain from douching or using powders.
  • Consider changing contraceptive methods if diaphragms, lubricated condoms, or spermicides cause irritation or recurrent infections.

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