Hemorrhoid Creams for Wrinkles 2025: Prices, Uses, and Side Effects Explained

You may have come across friends boasting flawless skin or seen celebrities like Kim Kardashian mention hemorrhoid creams as a wrinkle remedy. The idea that creams originally designed for hemorrhoids can reduce wrinkles, especially crow's feet around the eyes, has become a popular internet rumor. But what’s the real story behind this claim?

Scientific Perspective: Can Hemorrhoid Creams Actually Reduce Wrinkles?

The theory is that hemorrhoid creams such as Preparation H work by constricting blood vessels and tightening skin around the anus, which might translate into tightening effects on facial skin. This concept stems from an older version of Preparation H containing live yeast-cell derivative (LYCD), believed to promote skin tightening. However, no clinical studies confirm LYCD’s effectiveness in diminishing facial fine lines or wrinkles. While LYCD has been proven to aid in wound and burn healing, its anti-aging benefits remain unverified.

Since the 1990s, LYCD has been removed from hemorrhoid creams in the U.S. due to FDA concerns about its safety and efficacy. Modern formulations now typically contain phenylephrine, a vasoconstrictor that reduces blood vessel size, or hydrocortisone, a steroid that alleviates inflammation and itching.

Some dermatologists suggest phenylephrine may temporarily reduce puffiness around the eyes, but hydrocortisone can have adverse effects on facial skin if used long-term.

How to Safely Use Hemorrhoid Creams for Wrinkles

If you're curious about trying hemorrhoid creams for wrinkle reduction, look for the original Preparation H formula with Bio-Dyne (LYCD), which can sometimes be found through Canadian suppliers online. Always perform a patch test by applying a small amount to your inner wrist and waiting 20-30 minutes to check for any irritation or allergic reactions.

If no adverse effects occur, apply a thin layer gently to wrinkle-prone areas at night after cleansing your face. Avoid contact with eyes and wash your hands thoroughly afterward. Daytime use is possible but may leave a shiny or greasy appearance.

Keep in mind that consistent application over several weeks or months is necessary to observe any potential results, and even then, improvements are not guaranteed.

Potential Side Effects to Consider

Side effects vary depending on the cream’s active ingredients. Phenylephrine may cause temporary tightening but prolonged use can lead to thinner, more fragile, red, or swollen skin around the eyes.

Hydrocortisone creams can exacerbate skin conditions like acne, rosacea, and impetigo. The Mayo Clinic warns about skin thinning, easy bruising, and, in rare cases, systemic steroid effects impacting adrenal gland function when used extensively on the face.

Currently, there is no evidence that prolonged use of LYCD causes harmful side effects.

Final Verdict: Are Hemorrhoid Creams a Good Choice for Wrinkle Treatment?

There is limited scientific support for using hemorrhoid creams to reduce wrinkles. Most positive claims relate to outdated formulations containing LYCD, which are no longer widely available or approved. Using these creams long-term may damage skin integrity, increasing vulnerability to aging and sun damage.

For safer and more effective wrinkle prevention and treatment, focus on proven skincare habits: stay hydrated, wear sunscreen daily, and get adequate sleep. For existing wrinkles, consider dermatologist-recommended treatments such as microneedling, dermarolling, mild chemical peels, or products containing retinol, vitamin C, and hyaluronic acid.

Consult a skincare professional to tailor an anti-aging routine suited to your skin type and concerns.

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