Cabergoline 2025: Uses, Dosage, Side Effects & Price Guide

Key Facts About Cabergoline

1. Cabergoline is available exclusively as a generic oral tablet.
2. It is prescribed primarily to manage hyperprolactinemia, a condition characterized by elevated prolactin levels.
3. Cabergoline works by targeting dopamine receptors to reduce prolactin production.

Critical Safety Warnings

• Heart Valve Risks: This medication may cause heart valve complications. Regular heart monitoring, including echocardiograms, is essential before and during treatment. Avoid use if you have existing heart valve issues.
• Organ Fibrosis: Cabergoline can lead to tissue scarring in organs such as lungs, heart, or abdomen. Symptoms like persistent cough, chest pain, or swelling require immediate medical attention. Patients with a history of fibrosis should not take this drug.

What is Cabergoline?

Cabergoline is a prescription dopamine agonist available only as a generic tablet. It is designed for oral administration to treat elevated prolactin levels caused by pituitary gland disorders or tumors.

Therapeutic Uses

Primarily, Cabergoline treats hyperprolactinemia by lowering excess prolactin. Elevated prolactin can disrupt menstrual cycles and ovulation in women and impair sexual function in men, including decreased libido and erectile dysfunction.

Mechanism of Action

Cabergoline mimics dopamine, a natural neurotransmitter that inhibits prolactin secretion. By binding to dopamine receptors, it effectively reduces prolactin levels, restoring hormonal balance.

Common Side Effects of Cabergoline

Patients may experience mild side effects such as:

• Nausea
• Constipation
• Headache
• Dizziness
• Fatigue or weakness

These symptoms typically resolve within days to weeks. Persistent or severe side effects should be discussed with your healthcare provider.

Serious Side Effects

Seek immediate medical care if you experience:

• Breathing difficulties or persistent cough
• Chest pain or swelling of legs and feet
• Irregular heartbeats or swelling in limbs

Such symptoms may indicate severe organ or heart complications.

Drug Interactions

Cabergoline can interact adversely with certain medications, especially those that counteract its dopamine agonist effects. Avoid combining with:

• Antipsychotics (e.g., haloperidol, chlorpromazine)
• Anti-nausea drugs (e.g., metoclopramide, promethazine)

Always inform your doctor about all medications and supplements you are taking to prevent harmful interactions.

Important Precautions

Allergy Alert

Severe allergic reactions are rare but possible. Symptoms include breathing difficulty and throat swelling. Immediate emergency care is necessary if these occur.

Health Condition Warnings

• Do not use if you have uncontrolled hypertension or heart valve disease.
• Avoid if you have a history of tissue fibrosis or pregnancy-related high blood pressure.
• Consult your doctor if you have liver impairment, as dosage adjustments may be required.

Pregnancy and Breastfeeding

Cabergoline is categorized as pregnancy category B. Animal studies show no fetal risk, but human data is limited. Use only if clearly needed and under medical supervision. Breastfeeding mothers should discuss risks as the drug may affect milk production or pass into breast milk.

Use in Elderly and Children

Dosage adjustments may be necessary for seniors due to slower drug metabolism. Cabergoline is not recommended for individuals under 18 years old due to insufficient studies.

Recommended Dosage Guidelines

Dosage varies based on age, condition severity, and response to treatment.

• Adults (18-64 years): Starting dose is typically 0.25 mg twice weekly. Dose may be increased by 0.25 mg every 4 weeks, up to 1 mg twice weekly.
• Children: Not recommended.
• Seniors (65+ years): May require lower doses and careful monitoring.

Always follow your healthcare provider's instructions precisely.

Administration Tips

• Take with or without food.
• Tablets can be split or crushed if necessary.
• Maintain consistent dosing schedule for optimal effectiveness.

Storage and Handling

• Store at 20°C to 25°C (68°F to 77°F) in original container.
• Avoid moisture and extreme temperatures.
• Carry medication with you when traveling; keep in carry-on luggage.

Monitoring During Treatment

• Regular heart evaluations, including echocardiograms.
• Periodic blood tests to track prolactin levels.

Insurance and Availability

Cabergoline is generally covered by insurance but may require prior authorization. It is available only as a generic medication.

Alternative Treatments

Other dopamine agonists or therapies may be suitable alternatives. Consult your doctor to explore options tailored to your needs.

Note: This information is intended to complement, not replace, professional medical advice. Always consult your healthcare provider for personalized guidance.

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